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Investigación
El centro
Eventos y noticias
GENyO TV

WebMail
Área Privada

English

No se ha encontrado investigadores para este término.

Publicaciones

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Inicio - Investigación - Publicaciones

2025
2024
2023
Publicaciones anteriores

Melatonin Overcomes Cancer Multidrug Resistance by Downregulating ABCB1 Expression and Modulating Mitochondrial Function.

Autores: López-Rodríguez A, Martinez-Ruiz L, Morales-Gallel R, Florido J, Bermejo-Casares F, Garcia-Verdugo JM, Estebané MM, Carriel V, Maldonado-Pérez N, González-García P, Ahmadpour ST, Ramírez-Casas Y, Martín F, Dumas JF, Vandier C, Yang Y, Acuña-Castroviejo D, Escames G

11/2025 - Journal of pineal research

Extending Thioflavin T Fluorescence Probe to 2-Ethenyl-benzothiazole Derivatives: Drug-like Quadruplex Ligands with Potent Antitrypanosomatid Activity.

Autores: Gonçalves RCR, Peñalver P, Allen NM, Belmonte-Reche E, García-Pérez B, Costa SPG, Jiang YJ, Pérez-Victoria JM, Galan MC, Raposo MMM, Morales JC

11/2025 - ACS infectious diseases

Worldwide systematic analysis of dietary paraben exposure. A scoping review of sources and food categories.

Autores: González-Palacios P, Monteagudo C, Ramírez V, Zafra-Gómez A, Rivas A

10/2025 - Food chemistry

International expert consensus on the clinical integration of circulating tumor cells in solid tumors.

Autores: Nicolò E, Reduzzi C, Pierga JY, Gazzaniga P, Stoecklein NH, Denninghoff V, Rothwell DG, De Bono JS, Marchetti D, Lianidou E, Riethdorf S, Generali D, Hofman P, Gerratana L, Kuhn P, Thiery JP, Ignatiadis M, Bidard FC, Lucci A, Kasimir-Bauer S, Serrano MJ, Cristofanilli M

10/2025 - European journal of cancer (Oxford, England : 1990)

Custom Gene Panel Analysis Identifies Novel Polymorphisms Associated with Clopidogrel Response in Patients Undergoing Percutaneous Coronary Intervention with Stent.

Autores: Antúnez-Rodríguez A, García-Rodríguez S, Pozo-Agundo A, Sánchez-Ramos JG, Moreno-Escobar E, Triviño-Juárez JM, Álvarez-Cubero MJ, Martínez-González LJ, Dávila-Fajardo CL

10/2025 - International journal of molecular sciences

HLA molecules: Another challenge for CAR T cell therapy.

Autores: Salih I, Fakhkhari M, Berrougui H, Khalil A, Benabdellah K, Atilla E, Sadki K

10/2025 - Current research in translational medicine

Applying click chemistry principles to the design of tumor-targeted nanosystems.

Autores: Diaz-Mochon JJ, Sanchez-Martin RM

10/2025 - Nanomedicine (London, England)

A model including CD15, ACE2 and age efficiently predicts COVID-19 severity.

Autores: Cuenca-López S, Pozo-Agundo A, Morales-Álvarez CM, Arenas-Rodríguez V, Martínez-Diz S, Dávila-Fajardo CL, Álvarez-Cubero MJ, Martínez-González LJ

10/2025 - Scientific reports

Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus.

Autores: Pérez-Carrasco V, Soriano-Lerma A, Guzzi C, García-Martín ML, Tello MJ, Linde-Rodríguez Á, Sánchez-Martín V, Ortiz-González M, PRECISESADS Clinical Consortium, Gutiérrez-Fernández J, Alarcón-Riquelme ME, Soriano M, Marañón C, García-Salcedo JA

09/2025 - Biomarker research

Modulation of Human Immune Cells by Propyl-Propane Thiosulfonate (PTSO) Inhibits Colorectal Tumor Progression in a Humanized Mouse Model.

Autores: Rodríguez-Sojo MJ, Gbati L, Molina-Tijeras JA, Ho-Plágaro A, Vezza T, López-Escánez L, Griñán-Lisón C, Marchal JA, Baños A, Rodríguez-Sánchez MJ, García-García J, Ruiz-Malagón AJ, Gálvez J, Rodríguez-Cabezas ME, Rodríguez-Nogales A

09/2025 - Nutrients

"Emergence of a CTX-M-15-producing multidrug-resistance Haemophilus parainfluenzae in Southern Spain".

Autores: Pérez-Vázquez M, Pérez-Carrasco V, Aguilera-Franco M, Lara N, Rivero-Rodríguez M, Navarro-Marí JM, Gutiérrez-Fernández J

09/2025 - European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Serum lipid levels and risk of lymphoid malignancies in the UK Biobank study.

Autores: Hermosa S, Benavente Y, Cabezudo E, Sainz J, Farràs M, Alemany L, Birmann BM, Casabonne D

09/2025 - British journal of cancer

Tracker Nanocatalyst for Screening of Intracellular Copper-Catalyzed Azide-Alkyne Cycloadditions.

Autores: Rodríguez-Segura M, López-Delgado FJ, Cano-Cortés MV, Delgado-González A, Diaz-Mochon JJ, Sanchez-Martin RM

10/2025 - Small (Weinheim an der Bergstrasse, Germany)

Tigecycline suppresses colon cancer stem cells and impairs tumor engraftment by targeting SNAI1-regulated epithelial-mesenchymal transition.

Autores: Ruiz-Malagón AJ, Rodríguez-Sojo MJ, García-García J, Ho-Plagaro A, García F, Vezza T, Redondo-Cerezo E, Griñán-Lisón C, Marchal JA, Rodríguez-Cabezas ME, Rodríguez-Nogales A, Gálvez J

09/2025 - Acta pharmacologica Sinica

BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells.

Autores: Gallardo A, Belmonte-Reche E, Marti-Marimon M, Domingo-Reinés J, Peris G, López-Onieva L, Fernández-Rengel I, Xie J, Tristán-Ramos P, Bellora N, Sánchez-Pozo A, Estévez AM, Heras SR, Marti-Renom MA, Landeira D

09/2025 - Nature communications

A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers.

Autores: Cabrera-Serrano AJ, Ruiz-Durán L, Gutiérrez-Bautista JF, Carretero-Fernández M, Ter Horst R, Li Y, Reyes-Zurita FJ, García-Verdejo FJ, Netea MG, Sánchez-Rovira P, López-Nevot MÁ, Sampedro A, Sainz J

08/2025 - Frontiers in immunology

Discovery of core genes for systemic lupus erythematosus via genome-wide aggregated trans-effects analysis.

Autores: Iakovliev A, Castellini-Pérez O, Erabadda B, PRECISESADS Clinical Consortium, PRECISESADS Flow Cytometry Consortium, Martín J, Barturen G, McKeigue PM, Carnero-Montoro E, Alarcón-Riquelme ME, Spiliopoulou A

10/2025 - Genes and immunity

Identification of four autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia.

Autores: Cabrera-Serrano AJ, Sánchez-Maldonado JM, Rodríguez-Sevilla JJ, Reyes-Zurita FJ, Collado R, Puiggros A, Cornejo-Calvo E, García P, Ter Horst R, Benavente Y, Jerez A, Landi S, Espinet B, Maffei R, López-Nevot MÁ, Ramos-Campoy S, González-Olmedo C, Chen-Liang TH, Moreno V, Jannus F, Marcos-Gragera R, Carretero-Fernández M, Sampaio-Marques B, Gámez I, Garcia-Alvarez M, Camp NJ, Dierssen-Sotos T, Kamaso J, Pérez EM, Norman AD, Luppi M, Li Y, Alcoceba M, Campa D, de Sanjose S, Marasca R Prof, Ludovico P, Clay-Gilmour AI, Canzian F, Ibañez M, Netea MG, McKay J, Casabonne D, Berndt SI, Slager SL, Sainz J

09/2025 - Blood advances

PKP1 promotes lung cancer by modulating energy metabolism through stabilization of PFKP.

Autores: Ritoré-Salazar F, Arenas AM, Matia-González AM, Zaza A, Thomsen EA, Rovsing AB, Mikkelsen JG, Noguera NI, Medina PP

09/2025 - Biomarker research

High-fidelity Cas9-mediated targeting of KRAS driver mutations restrains lung cancer in preclinical models.

Autores: Álvarez-Pérez JC, Sanjuán-Hidalgo J, Arenas AM, Hernández-Navas I, Benitez-Cantos MS, Andrades A, Calabuig-Fariñas S, Jantus-Lewintre E, Paz-Ares L, Ferrer I, Medina PP

09/2025 - Nature communications

The effects of a supervised exercise training program during pregnancy on placental cytokines, and the potential role of fetal sex and maternal weight status.

Autores: Acosta-Manzano P, Flor-Alemany M, Martínez-González LJ, Alvarez-Cubero MJ, Baena-García L, Nestares T, Van Poppel MNM, Aparicio VA

09/2025 - Journal of sport and health science

Risk and Benefit Assessment of Gene Therapy with Lentiviral Vectors and Hematopoietic Stem Cells: The Skysona Case.

Autores: Puig-Serra P, Hinckley-Boned A, Tristán-Manzano M, Rio P, Torres-Ruiz R, Rodriguez-Perales S, Martín F

09/2025 - Human gene therapy

GSTM5 as a Potential Biomarker for Treatment Resistance in Prostate Cancer.

Autores: Porras-Quesada P, Chica-Redecillas L, Álvarez-González B, Gutiérrez-Tejero F, Arrabal-Martín M, Rios-Pelegrina R, Martínez-González LJ, Álvarez-Cubero MJ, Vázquez-Alonso F

08/2025 - Biomedicines

Amplification-Free Testing of microRNA Biomarkers in Cancer.

Autores: Soleimanpour B, Diaz Mochon JJ, Pernagallo S

08/2025 - Cancers

Regulatory Strategies for Accelerating the Translation of Gene Therapies to Clinical Practice: Focus on GMO Considerations.

Autores: Delgadillo J, Martin F, Carmona G, Canals JM, Rio P, Eguizabal C, Prosper F, Avendaño-Solá C

09/2025 - Human gene therapy

CD44-targeted N-benzyltetrahydroisoquinoline derivatives as anticancer agents with high tumor-to-normal cell selectivity.

Autores: Romero-Tamudo S, Carrión MD, Chayah M, Espejo-Román JM, Domene C, Sánchez-Martín RM, Cruz-López O, Conejo-García A

11/2025 - European journal of medicinal chemistry

Off-target effects in CRISPR-Cas genome editing for human therapeutics: Progress and challenges.

Autores: Kalter N, Fuster-García C, Silva A, Ronco-Díaz V, Roncelli S, Turchiano G, Gorodkin J, Cathomen T, Benabdellah K, Lee C, Hendel A

07/2025 - Molecular therapy. Nucleic acids

Optimized network inference for immune diseased single cells.

Autores: Tejero EM, Vaz DJ, Barturen G, Rivas-Torrubia M, Alarcón-Riquelme ME, Kolch W, Matallanas D

07/2025 - Frontiers in immunology

Bank1 deficiency reshapes the gut microbiota of lupus mice towards an anti-inflammatory composition.

Autores: Galicia G, Botía-Sánchez M, Toro-Dominguez D, García AL, Valera JR, Gómez Hernández G, Fernandez RM, Carmona N, Luque G, Morell M, Varela N, Pérez-Cozar F, Margolles A, Aguilera M, Alarcón-Riquelme ME

07/2025 - Frontiers in immunology

The effect of Fe(3)O(4) biosynthesized through the green synthesis of Silybum marianum and HA in the targeted delivery of 5-Fluorouracil to HCT116 cell line.

Autores: Mansuryar A, Bourang S, Noruzpour M, Ebrahimi HA, Amani A, Granados-Principal S, Calahorra J

07/2025 - Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

The Value of MRI-Based Radiomics in Predicting the Pathological Nodal Status of Rectal Cancer: A Systematic Review and Meta-Analysis.

Autores: Luengo Gómez D, García Cerezo M, López Cornejo D, Salmerón Ruiz Á, González-Flores E, Melguizo Alonso C, Láinez Ramos-Bossini AJ, Prados J, Ortega Sánchez FG

07/2025 - Bioengineering (Basel, Switzerland)

Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus.

Autores: Garantziotis P, Beretta L, Lindblom J, Moysidou GS, Nikolopoulos D, Grieshaber-Bouyer R, Hagen M, Bergmann C, Wirsching A, Bozec A, PRECISESADS Clinical Consortium, Schneider M, Barturen G, Bertsias G, Boumpas DT, Alarcón-Riquelme ME, Mackensen A, Schett G, Parodis I

07/2025 - Annals of the rheumatic diseases

MT2 receptor mediates melatonin-induced thermogenic program in human myoblasts: insights for circadian syndrome and diabesity treatment.

Autores: Salagre D, Sanjuán-Hidalgo J, Elmahallawy EK, Medina PP, Agil A

07/2025 - Frontiers in pharmacology

Insight into the epigenetic regulation of gene expression in the bloodstream and procyclic forms of Trypanosoma brucei through the involvement of G-quadruplexes.

Autores: Belmonte-Reche E, Martínez-García M, de Jong A, Kuipers OP, Cebrián R

07/2025 - NAR genomics and bioinformatics

Dysregulation of innate and adaptive lymphoid immunity may have implications for symptom attribution and predict responses to targeted therapies in neuropsychiatric systemic lupus erythematosus.

Autores: Lindblom J, Barturen G, Beretta L, Toro-Domínguez D, Carnero-Montoro E, Borghi MO, Castillo J, Iacobaeus E, Enman Y, PRECISESADS Clinical Consortium, Mohan C, Alarcón-Riquelme ME, Nikolopoulos D, Parodis I

06/2025 - Journal of translational autoimmunity

Investigation of HLA-B -21 M/T Dimorphism and Its Potential Role in COVID-19.

Autores: Martín-Rodríguez D, Gutiérrez-Bautista JF, Bernal M, Rodriguez-Nicolas A, Vílchez JR, Marín-Sánchez A, Rosales-Castillo A, Sainz J, Cabrera-Serrano AJ, Ceron-Hernandez J, López-Nevot MÁ, Ruiz-Cabello F, Jiménez P

07/2025 - International journal of molecular sciences

Phenotypic Plasticity and Androgen Receptor Bypass Drive Cross-Resistance to Apalutamide in Castration-Resistant Prostate Cancer Cell Models.

Autores: Simon I, Sanchez-Manas JM, Perales S, Martinez-Navajas G, Ceron-Hernandez J, Real PJ

06/2025 - International journal of molecular sciences

The role of intestinal microbiota in the humoral response to SARS-CoV-2 after mRNA-1273 vaccination.

Autores: Tarriño M, Gutiérrez-Bautista JF, Durán MJO, Garcia-Diaz A, Cabrera-Serrano AJ, Sainz J, Cobo F, Rodriguez T, Reguera JA, Bernal M, López-Nevot MÁ, Sampedro A

07/2025 - Scientific reports

Bisphenol A exposure and behavioral outcomes in children: A systematic review and meta-analysis of evidence limited to the BASC assessment tool.

Autores: González-Palacios P, Ramírez V, Monteagudo C, Zafra-Gómez A, Rivas A

09/2025 - Neuroscience and biobehavioral reviews

Signature-based repurposed drugs resemble the inhibition of TGFβ-induced NDRG1 as potential therapeutics for triple-negative breast cancer.

Autores: López-Tejada A, Blaya-Cánovas JL, Cara FE, Calahorra J, Ramírez-Tortosa C, Blancas I, Delgado-Almenta V, Muñoz-Parra F, Ávalos-Moreno M, Sánchez A, González-González A, Marchal JA, Griñán-Lisón C, Granados-Principal S

06/2025 - International journal of biological sciences

Autophagy and oxidative stress in solid tumors: Mechanisms and therapeutic opportunities.

Autores: Carretero-Fernández M, Cabrera-Serrano AJ, Sánchez-Maldonado JM, Ruiz-Durán L, Jiménez-Romera F, García-Verdejo FJ, González-Olmedo C, Cardús A, Díaz-Beltrán L, Gutiérrez-Bautista JF, Benavente Y, Gálvez-Montosa F, López-López JA, García-Martín P, Pérez EM, Rodríguez-Sevilla JJ, Casabonne D, Sánchez-Rovira P, Reyes-Zurita FJ, Sainz J

08/2025 - Critical reviews in oncology/hematology

Near-Infrared Light-Accelerated Bioorthogonal Drug Uncaging and Photothermal Ablation by Anisotropic Pd@Au Plasmonic Nanorods.

Autores: Ortega-Liebana MC, Travnickova J, Adam C, González-Calderón D, Lorente-Macías Á, Lochenie C, Arenal R, Patton EE, Unciti-Broceta A

07/2025 - Journal of the American Chemical Society

Pharmacogenetic Implementation Studies-Lessons Learned From the PREPARE Study.

Autores: Guchelaar HJ, van der Wouden CH, Manson LEN, Abdullah-Koolmees H, Blagec K, Blagus T, Böhringer S, Cecchin E, Cheung KC, Deneer VHM, Jonsson S, Joefield-Roka C, Just KS, Karlsson MO, Konta L, Koopmann R, Kriek M, Lehr T, Mitropoulou C, Rollinson V, Roncato R, Samwald M, Schaeffeler E, Skokou M, Schwab M, Steinberger D, Stingl JC, Tremmel R, Turner RM, van Rhenen MH, Dávila-Fajardo CL, Dolžan V, Patrinos GP, Pirmohamed M, Sunder-Plassmann G, Toffoli G, Swen JJ, Ubiquitous Pharmacogenomics Consortium

10/2025 - Clinical pharmacology and therapeutics

In-depth analysis of the mode of action of resveratrol: genome-wide characterization of G-quadruplex binding properties.

Autores: Soriano-Lerma A, Sánchez-Martín V, Murciano-Calles J, Ortiz-González M, Tello-López MJ, Pérez-Carrasco V, Linde-Rodríguez Á, Ramírez-Macías I, Gómez-Pìnto I, López-Aliaga I, Soriano M, Garcia Salcedo JA

06/2025 - Cellular & molecular biology letters

International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors.

Autores: Fusco N, Venetis K, Pepe F, Shetty O, Farinas SC, Heeke S, Burnier JV, Patton SJ, Heitzer E, Nigita G, Hofman P, Serrano MJ, Cristofanilli M, Jantus-Lewintre E, Gandara DR, Rolfo C, Malapelle U

05/2025 - The journal of liquid biopsy

Integration of T cell repertoire, CyTOF, genotyping and symptomatology data reveals subphenotypic variability in COVID-19 patients.

Autores: Marín-Benesiu F, Chica-Redecillas L, Cuenca-López S, Entrala-Bernal C, Martín-Esteban S, Alvarez-Cubero MJ, Martínez-González LJ

05/2025 - Computational and structural biotechnology journal

Cross-talk between NLRP3 and AIM2 inflammasomes in macrophage activation by LPS and titanium ions.

Autores: Carrillo-Gálvez AB, Guerra-Valverde JA, Padial-Molina M, Martínez-Cuevas A, Abril-García D, Olaechea A, Martín-Morales N, O'Valle F, Galindo-Moreno P, Zurita F

06/2025 - Molecular medicine (Cambridge, Mass.)

High-Dimensional Immunophenotyping of Post-COVID-19 and Post-Influenza Patients Reveals Persistent and Specific Immune Signatures After Acute Respiratory Infection.

Autores: Pérez-Cózar F, Cal-Sabater P, Rybakowska P, Arribas-Rodríguez E, Fiz-López A, García-Blesa A, Hernández J, Gutiérrez S, Tellería P, Novoa C, Rello SR, De Prado Á, Pérez C, Sedano R, Domínguez-Gil M, Peñarrubia MJ, Pieren DKJ, Garrote JA, Arranz E, Eiros JM, Tamayo E, Orduña A, van Els CACM, Dueñas C, Marañón C, Bernardo D, Cuesta-Sancho S

06/2025 - Journal of medical virology

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.

Autores: Wiley MM, Radziszewski M, Khatri B, Joachims ML, Tessneer KL, Stolarczyk AM, Yao S, Li J, Pritchett-Frazee C, Johnston AA, Rasmussen A, Anaya JM, Aqrawi LA, Bae SC, Baecklund E, Björk A, Brun JG, Bucher SM, Dand N, Eloranta ML, Engelke F, Forsblad-d'Elia H, Fugmann C, Glenn SB, Gong C, Gottenberg JE, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kelly JA, Khanam S, Kim K, Kvarnström M, Mandl T, Martín J, Morris DL, Nocturne G, Norheim KB, Olsson P, Palm Ø, Pers JO, Rhodus NL, Sjöwall C, Skarstein K, Taylor KE, Tombleson P, Thorlacius GE, Venuturupalli SR, Vital EM, Wallace DJ, Radfar L, Brennan MT, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Appel S, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner BM, Rischmueller M, Witte T, Farris AD, Mariette X, Shiboski CH, Sjögren’s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius M, Alarcón-Riquelme ME, PRECISESADS Clinical Consortium, Ng WF, UK Primary Sjögren’s Syndrome Registry, Sivils KL, Guthridge JM, Adrianto I, Vyse TJ, Tsao BP, Nordmark G, Lessard CJ

09/2025 - Annals of the rheumatic diseases

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole-Blood Transcriptomics Data.

Autores: Yap CF, Nair N, Morgan AW, Isaacs JD, Wilson AG, Hyrich K, Barturen G, Riva-Torrubia M, Gut M, Gut I, Alarcón Riquelme ME, Barton A, Plant D

05/2025 - Arthritis & rheumatology (Hoboken, N.J.)

Loss of the extracellular protease ADAMTS1 reveals an antitumorigenic program involving the action of NIDOGEN-1 on macrophage polarization.

Autores: Caracuel-Peramos R, Rodríguez-Baena FJ, Redondo-García S, Villatoro-García JA, García-Muñoz A, Peris-Torres C, Plaza-Calonge MDC, Rubio-Gayarre A, López-Millán B, Ricciardelli C, Russell DL, Carmona-Sáez P, Rodríguez-Manzaneque JC

12/2025 - Oncoimmunology

New IgG and IgA autoantibody specificities against DNA-binding and RNA-binding proteins discriminate systemic lupus erythematosus from health and non-lupus autoimmunity-could anti-LIN28A enhance precision in diagnostics?

Autores: Parodis I, Lagutkin D, Lindblom J, Idborg H, Beretta L, Borghi MO, PRECISESADS Clinical Consortium, Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Sherina N, Nikolopoulos D

07/2025 - Annals of the rheumatic diseases

The potential application of stroma modulation in targeting tumor cells: Focus on pancreatic cancer and breast cancer models.

Autores: Roscigno G, Jacobs S, Toledo B, Borea R, Russo G, Pepe F, Serrano MJ, Calabrò V, Troncone G, Giovannoni R, Giovannetti E, Malapelle U

08/2025 - Seminars in cancer biology

The exposome and pancreatic cancer, lifestyle and environmental risk factors for PDAC.

Autores: Peduzzi G, Archibugi L, Farinella R, Ponz de Leon Pisani R, Vodickova L, Vodicka P, Kraja B, Sainz J, Bars-Cortina D, Daniel N, Silvestri R, Uysal-Onganer P, Landi S, Dulińska-Litewka J, Comandatore A, Campa D, Hughes DJ, Rizzato C

08/2025 - Seminars in cancer biology

Hair as an Indicator of Prolonged Paraben Exposure and Its Relation to Weight Gain in a Sample of Spanish Children: A Proof-of-Concept Study.

Autores: Gálvez-Ontiveros Y, González-Palacios P, Ramírez V, Monteagudo C, Samaniego-Sánchez C, Rivas A, Zafra-Gómez A

05/2025 - Nutrients

EVs Biodistribution and Antifibrotic Impact in Aged Lung Fibrosis Model.

Autores: Amtil-Ouahdi I, Vergara F, Rio C, González-Martínez C, Jahn A, Forteza-Genestra MA, Gayá A, Calvo J, Sala-Llinas E, Navarrete BA, Romero-Ortiz AD, Monjo M, Ramis JM, Ortega FG

05/2025 - BioFactors (Oxford, England)

Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1.

Autores: Lindblom J, Lagutkin D, Sherina N, Idborg H, Beretta L, Borghi MO, PRECISESADS Clinical Consortium, Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Nikolopoulos D, Parodis I

07/2025 - Annals of the rheumatic diseases

Peak analysis of cell-free RNA finds recurrently protected narrow regions with clinical potential.

Autores: Bao P, Wang T, Liu X, Xing S, Ruan H, Ma H, Tao Y, Zhan Q, Belmonte-Reche E, Qin L, Han Z, Mao M, Li M, Lu ZJ

05/2025 - Genome biology

Tailoring CAR surface density and dynamics to improve CAR-T cell therapy.

Autores: Hinckley-Boned A, Barbero-Jiménez C, Tristán-Manzano M, Maldonado-Perez N, Hudecek M, Justicia-Lirio P, Martin F

04/2025 - Journal for immunotherapy of cancer

Donor insertion into CX3CR1 allows epigenetic modulation of a constitutive promoter on hematopoietic stem cells and its activation upon myeloid differentiation.

Autores: Ramos-Hernández I, Fuster-García C, Aguilar-González A, Lozano-Vinagre ML, Guenechea-Amurrio G, Sanchez-Luque FJ, Gonçalves MAFV, Cathomen T, Muñoz P, Molina-Estévez FJ, Martín F

04/2025 - Nucleic acids research

A Combined Approach Using T2*-Weighted Dynamic Susceptibility Contrast MRI Perfusion Parameters and Radiomics to Differentiate Between Radionecrosis and Glioma Progression: A Proof-of-Concept Study.

Autores: Martínez Barbero JP, García FJP, López Cornejo D, García Cerezo M, Gutiérrez PMJ, Balderas L, Lastra M, Arauzo-Azofra A, Benítez JM, Ramos-Bossini AJL

04/2025 - Life (Basel, Switzerland)

Oncogenic KRAS(G12D) Transfer from Platelet-like Particles Enhances Proliferation and Survival in Non-Small Cell Lung Cancer Cells.

Autores: Ceron-Hernandez J, Martinez-Navajas G, Sanchez-Manas JM, Molina MP, Xie J, Aznar-Peralta I, Garcia-Diaz A, Perales S, Torres C, Serrano MJ, Real PJ

04/2025 - International journal of molecular sciences

Functional Characterization of miR-216a-5p and miR-125a-5p on Pancreatic Cancer Stem Cells.

Autores: Fenu G, Griñán-Lisón C, Etzi F, González-Titos A, Pisano A, Toledo B, Farace C, Sabalic A, Carrillo E, Marchal JA, Madeddu R

03/2025 - International journal of molecular sciences

Crosstalk Between Autophagy and Oxidative Stress in Hematological Malignancies: Mechanisms, Implications, and Therapeutic Potential.

Autores: Cabrera-Serrano AJ, Sánchez-Maldonado JM, González-Olmedo C, Carretero-Fernández M, Díaz-Beltrán L, Gutiérrez-Bautista JF, García-Verdejo FJ, Gálvez-Montosa F, López-López JA, García-Martín P, Pérez EM, Sánchez-Rovira P, Reyes-Zurita FJ, Sainz J

02/2025 - Antioxidants (Basel, Switzerland)

Electrochemical immunoplatform for the quantification of epithelial extracellular vesicles applied to prostate cancer diagnosis.

Autores: Felici E, González-Martínez C, Griñán TV, Gato-Zambrano S, Pereira SV, Fernández-Baldo MA, Ortega-Sanchez FG

10/2025 - Talanta

The Value of Cerebral Blood Volume Derived from Dynamic Susceptibility Contrast Perfusion MRI in Predicting IDH Mutation Status of Brain Gliomas-A Systematic Review and Meta-Analysis.

Autores: Martínez Barbero JP, Pérez García FJ, Jiménez Gutiérrez PM, García Cerezo M, López Cornejo D, Olivares Granados G, Benítez JM, Láinez Ramos-Bossini AJ

04/2025 - Diagnostics (Basel, Switzerland)

Long-read genome and RNA sequencing resolve a pathogenic intronic germline LINE-1 insertion in APC.

Autores: Baumann AA, Knol LI, Arlt M, Hutschenreiter T, Richter A, Widmann TJ, Franke M, Hackmann K, Winkler S, Richter D, Spier I, Aretz S, Aust D, Porrmann J, William D, Schröck E, Glimm H, Jahn A

04/2025 - NPJ genomic medicine

A novel colorimetric assay for early differentiation of mucocutaneous and cutaneous leishmaniasis via species-specific identification.

Autores: Villao NV, Tabraue-Chavez M, Megino-Luque C, Aguilar-Gonzalez A, Guardia-Monteagudo JJ, Lopez-Delgado FJ, Robles-Remacho A, Cano-Cortés V, Diaz-Mochon JJ, Sanchez-Martin RM, Pernagallo S

10/2025 - Talanta

Exploring Trisubstituted adenine derivatives as adenosine A(1) receptor ligands with antagonist activity: Synthesis, biological evaluation and molecular modelling.

Autores: Córdoba-Gómez LB, Lorente-Macías Á, Loza MI, Brea J, Martínez AL, Mok J, King B, Franco-Montalban F, García AG, Guardia-Monteagudo JJ, Matos MJ, Unciti-Broceta A, Díaz-Mochón JJ, Las Infantas MJP

06/2025 - Bioorganic chemistry

An Overview and Comparative Analysis of CRISPR-SpCas9 gRNA Activity Prediction Tools.

Autores: Yuan H, Song C, Xu H, Sun Y, Anthon C, Bolund L, Lin L, Benabdellah K, Lee C, Hou Y, Gorodkin J, Luo Y

04/2025 - The CRISPR journal

DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects.

Autores: Colomer-Boronat A, Knol LI, Peris G, Sanchez L, Peluso S, Tristan-Ramos P, Gazquez-Gutierrez A, Chin P, Gordon K, Barturen G, Hill RE, Sanchez-Luque FJ, Garcia-Perez JL, Ivens A, Macias S, Heras SR

03/2025 - Nucleic acids research

Variability of COVID-19 mortality in Honduras: influence of sociodemographic factors.

Autores: Escoto Rodríguez VC, Expósito Ruiz M

03/2025 - International journal for equity in health

Cancer Vaccines and Beyond: The Transformative Role of Nanotechnology in Immunotherapy.

Autores: Delgado-Almenta V, Blaya-Cánovas JL, Calahorra J, López-Tejada A, Griñán-Lisón C, Granados-Principal S

02/2025 - Pharmaceutics

Exploring miR-21 Knock-Out Using CRISPR/Cas as a Treatment for Lung Cancer.

Autores: Lara P, Aguilar-González A, Martín F, Mesas C, Moreno J, Rama AR

01/2025 - Genes

Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group.

Autores: Cavazza A, Molina-Estévez FJ, Reyes ÁP, Ronco V, Naseem A, Malenšek Š, Pečan P, Santini A, Heredia P, Aguilar-González A, Boulaiz H, Ni Q, Cortijo-Gutierrez M, Pavlovic K, Herrera I, de la Cerda B, Garcia-Tenorio EM, Richard E, Granados-Principal S, López-Márquez A, Köber M, Stojanovic M, Vidaković M, Santos-Garcia I, Blázquez L, Haughton E, Yan D, Sánchez-Martín RM, Mazini L, Aseguinolaza GG, Miccio A, Rio P, Desviat LR, Gonçalves MAFV, Peng L, Jiménez-Mallebrera C, Molina FM, Gupta D, Lainšček D, Luo Y, Benabdellah K

01/2025 - Molecular therapy. Nucleic acids

The histone deacetylase inhibitor Scriptaid targets G-quadruplexes.

Autores: Sanchez-Martin V, Ruzic D, Tello-Lopez MJ, Ortiz-Morales A, Murciano-Calles J, Soriano M, Nikolic K, Garcia-Salcedo JA

02/2025 - Open biology

Transcriptomics and epigenomics datasets of primary brain cancers in formalin-fixed paraffin embedded format.

Autores: García-Heredia A, Guerra-Núñez L, Martín-Climent P, Rojas E, López-Domínguez R, Alcántara-Domínguez C, Alenda C, Valor LM

02/2025 - Scientific data

Enhancing Genetic Studies on Rheumatic Diseases in Latin America: The IARGE-RD Initiative.

Autores: Durán J, Pons-Estel BA, Alarcón-Riquelme ME, Díaz Peña R

06/2025 - The Journal of rheumatology

Virtual patients inspired by multiomics predict the efficacy of an anti-IFNα mAb in cutaneous lupus.

Autores: Hurez V, Gauderat G, Soret P, Myers R, Dasika K, Sheehan R, Friedrich C, Reed M, Laigle L, Riquelme MA, Aussy A, Chadli L, Hubert S, Desvaux E, Fouliard S, Moingeon P, PRECISESADS Clinical Consortium

01/2025 - iScience

New N-Alkylketonetetrahydroisoquinoline derivatives exhibits antitumor effect by HA-CD44 interaction inhibition in MDA-MB-231 breast cancer.

Autores: Chayah M, Espejo-Román JM, Erviti-Marticorena L, Huertas-Camarasa F, Domene C, Sánchez-Martín RM, Conejo-García A, Cruz-López O

03/2025 - Bioorganic chemistry

Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk of Cancer.

Autores: Puri A, Yin Z, Granados-Principal S, Ensor J, Guzman L, Rosato R, Zhao H, Wong S, Wang L, Patel T, Chang JC

01/2025 - International journal of breast cancer

Role of the International Society of Liquid Biopsy (ISLB) in establishing quality control frameworks for clinical integration.

Autores: Fusco N, Jantus-Lewintre E, Serrano MJ, Gandara D, Malapelle U, Rolfo C

05/2025 - Critical reviews in oncology/hematology

Dendritic Platinum Nanoparticles Shielded by Pt-S PEGylation as Intracellular Reactors for Bioorthogonal Uncaging Chemistry.

Autores: Garcia-Peiro JI, Ortega-Liebana MC, Adam C, Lorente-Macías Á, Travnickova J, Patton EE, Guerrero-López P, Garcia-Aznar JM, Hueso JL, Santamaria J, Unciti-Broceta A

04/2025 - Angewandte Chemie (International ed. in English)

BiomiX, a user-friendly bioinformatic tool for democratized analysis and integration of multiomics data.

Autores: Iperi C, Fernández-Ochoa Á, Barturen G, Pers JO, Foulquier N, Bettacchioli E, Alarcón-Riquelme M, PRECISESADS Flow Cytometry Study Group, PRECISESADS Clinical Consortium, Cornec D, Bordron A, Jamin C

01/2025 - BMC bioinformatics

De novo lipogenesis protects dormant breast cancer cells from ferroptosis and promotes metastasis.

Autores: Puente-Cobacho B, Esteo C, Altea-Manzano P, Garcia-Perez JL, Quiles JL, Sanchez-Rovira P, Martín-Salvago MD, Molina-Jiménez L, Luque RJ, Fendt SM, Vera-Ramirez L

03/2025 - Redox biology

Evaluating MicroRNAs as diagnostic tools for lymph node metastasis in breast cancer: Findings from a systematic review and meta-analysis.

Autores: Martínez CG, Therapontos S, Lorente JA, Lucena MA, Ortega FG, Serrano MJ

03/2025 - Critical reviews in oncology/hematology

Revisiting the heterogeneity of interferon-related autoimmune diseases.

Autores: Barturen G, Alarcón-Riquelme ME

01/2025 - Nature reviews. Rheumatology

Resectable Non-Small Cell Lung Cancer Heterogeneity and Recurrence Assessed by Tissue Next-Generation Sequencing Genotyping and Circulating Tumor Cell EZH2 Characterization.

Autores: Garcia-Diaz A, Moyano-Rodríguez MJ, Garrido-Navas MDC, de Miguel-Perez D, Expósito-Hernández J, Alcázar-Navarrete B, Ortuño F, Landeira D, Romero PJ, Garcia-Moreno A, Lorente JA, Lopez-Hidalgo J, Bayarri-Lara C, Serrano MJ

03/2025 - Archivos de bronconeumologia

Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization.

Autores: Gálvez-Montosa F, Peduzzi G, Sanchez-Maldonado JM, Ter Horst R, Cabrera-Serrano AJ, Gentiluomo M, Macauda A, Luque N, Ünal P, García-Verdejo FJ, Li Y, López López JA, Stein A, Bueno-de-Mesquita HB, Arcidiacono PG, Zanette DL, Kahlert C, Perri F, Soucek P, Talar-Wojnarowska R, Theodoropoulos GE, Izbicki JR, Tamás H, Van Laarhoven H, Nappo G, Petrone MC, Lovecek M, Vermeulen RCH, Adamonis K, Reyes-Zurita FJ, Holleczek B, Sumskiene J, Mohelníková-Duchoňová B, Lawlor RT, Pezzilli R, Aoki MN, Pasquali C, Petrenkiene V, Basso D, Bunduc S, Comandatore A, Brenner H, Ermini S, Vanella G, Goetz MR, Archibugi L, Lucchesi M, Uzunoglu FG, Busch O, Milanetto AC, Puzzono M, Kupcinskas J, Morelli L, Sperti C, Carrara S, Capurso G, van Eijck CHJ, Oliverius M, Roth S, Tavano F, Kaaks R, Szentesi A, Vodickova L, Luchini C, Schöttker B, Landi S, Dohan O, Tacelli M, Greenhalf W, Gazouli M, Neoptolemos JP, Cavestro GM, Boggi U, Latiano A, Hegyi P, Ginocchi L, Netea MG, Sánchez-Rovira P, Canzian F, Campa D, Sainz J

01/2025 - International journal of cancer