NANOCHEMBIO: Development of therapeutic and diagnosis strategies

Home Research groups NANOCHEMBIO: Development of therapeutic and diagnosis strategies

NANOCHEMBIO: Development of therapeutic and diagnosis strategies

Dra. Rosario María Sánchez Martín

Scientific interest areas

Chemical Biology, nanotechnology, nanotoxicology, nanosafety, characterisation of nanomaterials, biomedicine, molecular diagnosis, personalized medicine, biomaterials.

Research areas

  • Strategies for nanosphere?Mediated Cellular Control – generation of induced pluripotent stem cells for Regenerative Medicine.
  • Selective antitumoral therapy based on the use of nanodevices.
  • Nanotoxicology / Nanosafety.
  • Preclinical evaluation.
  • Development and application of nanotechnology approaches for efficient targeted delivery of drugs to central nervious system (CNS).
  • Chemical-based platforms for miRNA detection.
  • Integration of nanotechnology with dynamic chemistry for in situ miRNA analysis.
  • Development of biomaterials for cellular and protein control.

Technology platforms

    • Nanotechnology Platforms for selective delivery of therapeutic agents
    • HTS Platforms for biological systems
    • PCR-free Diagnostic Platforms for nucleic acid testing
    • Solid phase synthesis Platform- preparation of peptide, nucleic acid mimics and peptidomimetics
    • Biomaterial Platform for developing SMART materials
    • Preclinical evaluation Unit of nanomaterials

Funding

    • Agencia Ejecutiva de Investigación (REA) de la Comunidad Europea
    • Ministerio de Economía y Competitividad
    • Consejería de Innovación, Ciencia y Empresa, Junta de Andalucía

Research group patents

Application Number: P201431357
Priority Date: 18/09/2014
Title: Procedure to detect circulating tumor cells, both circulating tumors cells of epithelial phenotype and circulating tumour cells having Epithelial-mesenchymal transition markers (EMTs), by using miRNA-21 as a biomarker.
Authors: Serrano,M.J., Diaz-Mochón, J.J, Ortega, F.G., Lorente, J.A. Garcia-Puche, J.L., Ruiz-Blas, M.P., Sánchez-Martín, R.M.

Application Number: WO2015140386-A1; ES2548927-A1
Priority Date:
21/03/2014
Title: 
New purine derivative, useful for preparing pharmaceutical composition or medicament for treating disease or condition mediated by death-associated protein kinase 1 (DAPK1), preferably cancer and leukemia
Authors: 
Molina Pineda de las Infantas, I., Torres Rusillo, S., Fernandez, P., Pineda de las Infantas y Villatoro, M.J., Diaz-Mochón, J.J, Unciti-Broceta, A.

Nº Solicitud: GB 0718255.3
Priority Date: 17/09/2007
Title: Nucleobase Characterisation
Authors: Bradley, M and Díaz-Mochón, J.J.

Application Number: PCT/GB2008/003185
Priority Date: 17/09/2007
Title: Nucleobase Characterisation
Authors: Bradley, M and Díaz-Mochón, J.J.

Application Number: GB 0904834.9.
Priority Date: 20/03/2009
Title: Polymer for growing cells
Authors: Hay, D., Pernagallo, S., Díaz-Mochón, J.J., Bradley, M., Iredale, J.

Selected publications

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