Chemical Biology, nanotechnology, nanotoxicology, nanosafety, characterisation of nanomaterials, biomedicine, molecular diagnosis, personalized medicine, biomaterials.
Research areas
Selective antitumoral therapy based on the use of nanodevices.
Chemical-based platforms for nucleic acid detection in liquid biopsy.
Integration of nanotechnology with dynamic chemistry for in situ miRNA analysis.
Peptide nucleic acids based approaches for gene editing.
Development of chemical platforms for isolation
labelling and analysis of exosomes.
Optimizacion of chemical strategies for selective drug release.
Nanotoxicology / Nanosafety.
Preclinical evaluation of nanodevices.
Development of biomaterials for cellular and protein control.
Technology platforms
Nanotechnology Platforms for selective delivery of therapeutic agents
HTS Platforms for biological systems
PCR-free Diagnostic Platforms for nucleic acid testing
Solid phase synthesis Platform- preparation of peptide, nucleic acid mimics and peptidomimetics
Biomaterial Platform for developing SMART materials
Preclinical evaluation Unit of nanomaterials
Funding
Agencia Ejecutiva de Investigación (REA) de la Comunidad Europea
Ministerio de Economía y Competitividad
Consejería de Innovación, Ciencia y Empresa, Junta de Andalucía
Research group patents
Application Number:P201431357 Priority Date:18/09/2014 Title: Procedure to detect circulating tumor cells, both circulating tumors cells of epithelial phenotype and circulating tumour cells having Epithelial-mesenchymal transition markers (EMTs), by using miRNA-21 as a biomarker. Authors:Serrano,M.J., Diaz-Mochón, J.J, Ortega, F.G., Lorente, J.A. Garcia-Puche, J.L., Ruiz-Blas, M.P., Sánchez-Martín, R.M.
Application Number:WO2015140386-A1; ES2548927-A1 Priority Date: 21/03/2014 Title:New purine derivative, useful for preparing pharmaceutical composition or medicament for treating disease or condition mediated by death-associated protein kinase 1 (DAPK1), preferably cancer and leukemia Authors:Molina Pineda de las Infantas, I., Torres Rusillo, S., Fernandez, P., Pineda de las Infantas y Villatoro, M.J., Diaz-Mochón, J.J, Unciti-Broceta, A.
Nº Solicitud:GB 0718255.3 Priority Date:17/09/2007 Title:Nucleobase Characterisation Authors:Bradley, M and Díaz-Mochón, J.J.
Application Number:PCT/GB2008/003185 Priority Date:17/09/2007 Title:Nucleobase Characterisation Authors:Bradley, M and Díaz-Mochón, J.J.
Application Number:GB 0904834.9. Priority Date:20/03/2009 Title:Polymer for growing cells Authors:Hay, D., Pernagallo, S., Díaz-Mochón, J.J., Bradley, M., Iredale, J.